Mapping Data Summary

• Symbol: Adam17
• Name: a disintegrin and metallopeptidase domain 17
• ID: MGI:1096335
• Chromosome: 12

9 mapping experiments

Experiment Type	Details	Chromosome	Reference
CROSS	Cross Type: Backcross Mapping Panel: Copeland-Jenkins	12	J:57143 Cerretti DP, et al., Characterization of the cDNA and gene for mouse tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and its location to mouse chromosome 12 and human chromosome 2p25. Cytokine. 1999 Aug;11(8):541-51
CROSS	Cross Type: Backcross	12	J:160781 Hassemer EL, et al., The waved with open eyelids (woe) locus is a hypomorphic mouse mutation in Adam17. Genetics. 2010 May;185(1):245-55
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	12	J:59904 Wagener R, et al., Structure and mapping of the mouse matrilin-3 gene (Matn3), a member of a gene family containing a U12-type AT-AC intron. Mamm Genome. 2000 Feb;11(2):85-90
CROSS	Cross Type: Backcross Mapping Panel: JAX (BSS)	12	J:47651 Yamazaki K, et al., Genetic mapping of mouse tumor necrosis factor-alpha converting enzyme (TACE) to chromosome 12. Genomics. 1998 Apr 15;49(2):336-7
TEXT-QTL		12	J:56090 Mu JL, et al., Quantitative trait loci analysis for the differences in susceptibility to atherosclerosis and diabetes between inbred mouse strains C57BL/6J and C57BLKS/J. J Lipid Res. 1999 Jul;40(7):1328-35
TEXT-QTL		12	J:104621 Teupser D, et al., Atherosclerosis quantitative trait loci are sex- and lineage-dependent in an intercross of C57BL/6 and FVB/N low-density lipoprotein receptor-/- mice. Proc Natl Acad Sci U S A. 2006 Jan 3;103(1):123-8
TEXT-QTL-Candidate Genes		19	J:149028 Holdt LM, et al., Increased ADAM17 mRNA expression and activity is associated with atherosclerosis resistance in LDL-receptor deficient mice. Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1097-103
TEXT-QTL-Candidate Genes		12	J:152405 Kurey I, et al., Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics. 2009 Sep;61(9):619-33
TEXT-Radiation Hybrid		12	J:68900 The Jackson Laboratory Mouse Radiation Hybrid Database, Mouse T31 Radiation Hybrid Data Load. Database Release. 2004;