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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    1
  • Reference
    J:197549 Rowlan JS, et al., New quantitative trait loci for carotid atherosclerosis identified in an intercross derived from apolipoprotein E-deficient mouse strains. Physiol Genomics. 2013 Apr 16;45(8):332-42
  • ID
    MGI:5693292
Genes
GeneAlleleAssay TypeDescription
Nhdlq13 visible phenotype
Notes
  • Experiment
    Linkage analysis was performed on 266 female (B6.129P2-Apoetm1Unc/J x C.129P2(B6)-Apoetm1Unc)F2 intercross mice using 130 SNP markers to identify QTL associated with non-HDL cholesterol level on a Western diet.

    QTL Nhdlq13 maps to 54.31 - 82.31 cM on Chromosome 1 with a peak LOD score of 5.93 at 60.31 cM in linkage with non-HDL cholesterol level. C.129P2(B6)-Apoetm1Unc alleles confer increased susceptibility to higher non-HDL cholesterol levels with a dominant mode of inheritance.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory