Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  13
• Reference
  J:197549 Rowlan JS, et al., New quantitative trait loci for carotid atherosclerosis identified in an intercross derived from apolipoprotein E-deficient mouse strains. Physiol Genomics. 2013 Apr 16;45(8):332-42
• ID
  MGI:5689900

Genes

Gene
Cath3

Notes

• Experiment
  Linkage analysis was performed on 266 female (B6.129P2-Apoe^tm1Unc/J x C.129P2(B6)-Apoe^tm1Unc)F2 intercross mice using 130 SNP markers to identify QTL associated with susceptibility to athleroscotic carotid lesion. QTL mapping was performed using a nonparametric method.
  
  QTL Cath3 maps to 18.99 - 59.69 cM on Chromosome 13 with a peak LOD score of 4.292 at 48.99 cM in linkage with athleroscotic carotid lesion incidence. B6.129P2-Apoe^tm1Unc/J alleles confer increased susceptibility to athleroscotic carotid lesion with an additive mode of inheritance.