Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:187953 Zhang Z, et al., Genetic analysis of atherosclerosis and glucose homeostasis in an intercross between C57BL/6 and BALB/cJ apolipoprotein E-deficient mice. Circ Cardiovasc Genet. 2012 Apr 1;5(2):190-201
• ID
  MGI:5661869

Genes

Gene	Assay Type
Bglu12	visible phenotype
D1Mit495

Notes

• Experiment
  Linkage analysis was performed on 266 female (B6.129P2-Apoe^tm1Unc/J x C.129P2(B6)-Apoe^tm1Unc)F2 intercross mice using 130 SNP markers to identify QTL associated with fasting plasma blood glucose level on a Chow diet.
  
  QTL Bglu12 maps to 48.3 - 78.3 cM on Chromosome 1 with a peak LOD score of 3.94 at D1Mit495 (60.3 cM) in linkage with plasma blood glucose level. C.129P2(B6)-Apoe^tm1Unc alleles confer increased susceptibility to higher plasma blood glucose levels on Chow diet with an additive mode ofinheritance.