Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  1
• Reference
  J:208464 Kayashima Y, et al., Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice. PLoS One. 2014;9(2):e88274
• ID
  MGI:5644457

Genes

Gene	Assay Type
Phdlc4	visible phenotype

Notes

• Experiment
  Linkage analysis was performed on 172 male (129S6/SvEvTac-Apoe^tm4Mae x D2.129P2(B6)-Apoe^tm1Unc/J)F2 intercross mice using 170 SNP markers to identify QTL associated with plasma HDL cholesterol level.
  
  QTL Phdlc4 maps to 27-47 Mb (36-64 cM) on Chromosome 1 with a peak LOD score of 3.9 at 126 Mb (48 cM) in linkage with plasma HDL cholesterol level. 129S6/SvEvTac-Apoe alleles confer increased plasma HDL cholesterol levels.