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Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    11
  • Reference
    J:208464 Kayashima Y, et al., Quantitative trait loci affecting atherosclerosis at the aortic root identified in an intercross between DBA2J and 129S6 apolipoprotein E-null mice. PLoS One. 2014;9(2):e88274
  • ID
    MGI:5644450
Genes
GeneAlleleAssay TypeDescription
Pcho3 visible phenotype
Notes
  • Experiment
    Linkage analysis was performed on 309 (172 males; 137 females) (129S6/SvEvTac-Apoetm4Mae x D2.129P2(B6)-Apoetm1Unc/J)F2 intercross mice using 170 SNP markers to identify QTL associated with total plasma cholesterol level.

    QTL Pcho3 maps to 71-83 Mb (43-50 cM) on Chromosome 11 with a peak LOD score of 6.4 at 83 Mb (50 cM) in linkage with total plasma cholesterol level. 129S6/SvEvTac-Apoe alleles confer increased total plasma cholesterol level.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory