Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  4
• Reference
  J:37223 Gould KA, et al., Genetic evaluation of candidate genes for the Mom1 modifier of intestinal neoplasia in mice. Genetics. 1996 Dec;144(4):1777-85
• ID
  MGI:48211

Genes

Gene	Assay Type	Description
D4Mit12	PCR amplified length variant
D4Mit249	PCR amplified length variant
D4Mit203	PCR amplified length variant
D4Mit71	PCR amplified length variant
D4Mit134	PCR amplified length variant
D4Mit68	PCR amplified length variant
D4Mit54	PCR amplified length variant
Rap1gap	Southern analysis	Rap-B6, Rap-AKR
Pla2g2a	visible phenotype
D4Mit170	PCR amplified length variant
D4Mit64	PCR amplified length variant
D4Mit284	PCR amplified length variant
D4Mit13	PCR amplified length variant

Notes

• Reference
  Author uses Pla2s to describe the Pla2g2a locus in tumor tissue.
• Experiment
  400 meioses were used to determine recombinant mice. Authors note that the single recombination event indicated in the cross data eliminates Rap1ga1 as a candidate for Mom1. Two recombinant mice exhibiting partial tumor resistance were given the AKR/J phenotype.

CROSS

• Type
  Backcross, female
• Female Parent
  <a> <a> <a> <a> <a> <a> <a> <a> <a> <a> <a> <a> <a> <a>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  (AKR/J x C57BL/6J-Apc)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Allele 1
  a from AKR/J
• Allele 2
  b from C57BL/6J

CROSS Data

MC #mice	D4Mit12	D4Mit249	D4Mit203	D4Mit71	D4Mit134	D4Mit68	D4Mit54	Rap1gap	Pla2g2a	D4Mit170	D4Mit64	D4Mit284	D4Mit13
1	a	b	b	b	b	b	b	b	b	b	b	b	b	b
1	b	b	b	b	b	b	b	b	b	b	b	b	b	a
1	b	b	b	b	b	b	b	b	a	a	a	a	a	a
1	b	b	b	b	a	a	a	a	a	a	a	a	a	a
1	b	b	b	a	a	a	a	a	a	a	a	a	a	a
1	a	a	a	a	a	a	a	a	a	a	a	a	b	b
1	a	a	a	a	a	a	a	a	a	a	a	a	b	b
1	b	b	a	a	a	a	a	a	a	a	a	a	b	b