Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  X
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48097

Genes

Gene	Assay Type
DXMit26	PCR amplified length variant
DXMit57	PCR amplified length variant
DXUcla1	reported elsewhere
Fdpsl9	reported elsewhere
DXMit1.1	PCR amplified length variant
DXUcla2	reported elsewhere
G6pdx	reported elsewhere
DXMit24	PCR amplified length variant
DXMit14	PCR amplified length variant
DXMit28	PCR amplified length variant
Plp1	reported elsewhere
Pou3f4	reported elsewhere

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/Y
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
DXMit26	DXMit57	9	57
DXMit57	DXUcla1	9	57
DXMit57	Fdpsl9	9	57
DXUcla1	Fdpsl9	0	66
DXUcla1	DXMit1.1	5	59
Fdpsl9	DXMit1.1	5	59
DXMit1.1	DXUcla2	2	58
DXUcla2	G6pdx	1	61
G6pdx	DXMit24	3	61
DXMit24	DXMit14	3	57
DXMit24	DXMit28	3	57
DXMit14	DXMit28	0	62
DXMit14	Plp1	1	64
DXMit28	Plp1	1	64
Plp1	Pou3f4	4	61

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
DXMit26	DXMit57	9	66	13.636	4.224
DXMit57	DXUcla1	9	66	13.636	4.224
DXMit57	Fdpsl9	9	66	13.636	4.224
DXUcla1	Fdpsl9	0	66	0.000	0.000
DXUcla1	DXMit1.1	5	64	7.812	3.355
Fdpsl9	DXMit1.1	5	64	7.812	3.355
DXMit1.1	DXUcla2	2	60	3.333	2.317
DXUcla2	G6pdx	1	62	1.613	1.600
G6pdx	DXMit24	3	64	4.688	2.642
DXMit24	DXMit14	3	60	5.000	2.814
DXMit24	DXMit28	3	60	5.000	2.814
DXMit14	DXMit28	0	62	0.000	0.000
DXMit14	Plp1	1	65	1.538	1.527
DXMit28	Plp1	1	65	1.538	1.527
Plp1	Pou3f4	4	65	6.154	2.981