Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  17
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48094

Genes

Gene	Assay Type
D17Ucla1	reported elsewhere
Fdpsl8	reported elsewhere
D17Mit18	PCR amplified length variant
Pim1	reported elsewhere
Clps	reported elsewhere
Ppard	reported elsewhere
D17Nds3	reported elsewhere
Rxrb	reported elsewhere
C3	reported elsewhere
D17Ucla2	reported elsewhere
D17Mit41	PCR amplified length variant
D17Ucla3	reported elsewhere

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D17Ucla1	Fdpsl8	5	61
D17Ucla1	D17Mit18	5	61
Fdpsl8	D17Mit18	0	65
Fdpsl8	Pim1	6	59
Fdpsl8	Clps	6	59
Fdpsl8	Ppard	6	59
D17Mit18	Pim1	6	59
D17Mit18	Clps	6	59
D17Mit18	Ppard	6	59
Pim1	Clps	0	66
Pim1	Ppard	0	66
Clps	Ppard	0	66
Pim1	D17Nds3	3	55
Clps	D17Nds3	3	55
Ppard	D17Nds3	3	55
D17Nds3	Rxrb	2	56
Rxrb	C3	11	53
Rxrb	D17Ucla2	11	53
C3	D17Ucla2	0	65
C3	D17Mit41	9	55
D17Ucla2	D17Mit41	9	55
D17Mit41	D17Ucla3	2	62

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D17Ucla1	Fdpsl8	5	66	7.576	3.257
D17Ucla1	D17Mit18	5	66	7.576	3.257
Fdpsl8	D17Mit18	0	65	0.000	0.000
Fdpsl8	Pim1	6	65	9.231	3.590
Fdpsl8	Clps	6	65	9.231	3.590
Fdpsl8	Ppard	6	65	9.231	3.590
D17Mit18	Pim1	6	65	9.231	3.590
D17Mit18	Clps	6	65	9.231	3.590
D17Mit18	Ppard	6	65	9.231	3.590
Pim1	Clps	0	66	0.000	0.000
Pim1	Ppard	0	66	0.000	0.000
Clps	Ppard	0	66	0.000	0.000
Pim1	D17Nds3	3	58	5.172	2.908
Clps	D17Nds3	3	58	5.172	2.908
Ppard	D17Nds3	3	58	5.172	2.908
D17Nds3	Rxrb	2	58	3.448	2.396
Rxrb	C3	11	64	17.188	4.716
Rxrb	D17Ucla2	11	64	17.188	4.716
C3	D17Ucla2	0	65	0.000	0.000
C3	D17Mit41	9	64	14.062	4.345
D17Ucla2	D17Mit41	9	64	14.062	4.345
D17Mit41	D17Ucla3	2	64	3.125	2.175