Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  16
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48093

Genes

Gene	Assay Type
D16Mit31	PCR amplified length variant
Igll1	reported elsewhere
D16Mit100	PCR amplified length variant
D16Ucla1	reported elsewhere
D16Mit1	PCR amplified length variant
D16Mit3	PCR amplified length variant
D16Mit5	PCR amplified length variant
D16Mit6	PCR amplified length variant

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D16Mit31	Igll1	10	53
Igll1	D16Mit100	2	60
Igll1	D16Ucla1	2	60
D16Mit100	D16Ucla1	0	65
D16Mit100	D16Mit1	1	62
D16Ucla1	D16Mit1	1	63
D16Mit1	D16Mit3	3	60
D16Mit3	D16Mit5	13	52
D16Mit5	D16Mit6	7	58

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D16Mit31	Igll1	10	63	15.873	4.604
Igll1	D16Mit100	2	62	3.226	2.244
Igll1	D16Ucla1	2	62	3.226	2.244
D16Mit100	D16Ucla1	0	65	0.000	0.000
D16Mit100	D16Mit1	1	63	1.587	1.575
D16Ucla1	D16Mit1	1	64	1.562	1.550
D16Mit1	D16Mit3	3	63	4.762	2.683
D16Mit3	D16Mit5	13	65	20.000	4.961
D16Mit5	D16Mit6	7	65	10.769	3.845