Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  9
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48086

Genes

Gene	Assay Type
Gria4	reported elsewhere
Ldlr	reported elsewhere
D9Mit2	PCR amplified length variant
Pou2f3	reported elsewhere
Oaf	reported elsewhere
Drd2	reported elsewhere
Apoa1	reported elsewhere
D9Mit27	PCR amplified length variant
Cryab	reported elsewhere
D9Ucla4	reported elsewhere
Lipc	reported elsewhere
D9Mit8	PCR amplified length variant
D9Ucla6	reported elsewhere
Slc38a3	reported elsewhere
D9Mit36	PCR amplified length variant
D9Ucla7	reported elsewhere
D9Mit19	PCR amplified length variant
D9Ucla3	reported elsewhere
D9Ucla5	reported elsewhere

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Gria4	Ldlr	5	59
Ldlr	D9Mit2	6	55
D9Mit2	Pou2f3	3	58
Pou2f3	Oaf	1	65
Oaf	Drd2	3	60
Oaf	Apoa1	3	60
Drd2	Apoa1	0	63
Drd2	D9Mit27	2	60
Drd2	Cryab	2	60
Apoa1	D9Mit27	2	60
Apoa1	Cryab	2	60
D9Mit27	Cryab	0	61
D9Mit27	D9Ucla4	4	61
Cryab	D9Ucla4	4	61
D9Ucla4	Lipc	5	61
Lipc	D9Mit8	1	51
D9Mit8	D9Ucla6	9	41
D9Ucla6	Slc38a3	6	58
D9Ucla6	D9Mit36	6	58
Slc38a3	D9Mit36	0	50
Slc38a3	D9Ucla7	3	47
D9Mit36	D9Ucla7	3	47
D9Ucla7	D9Mit19	1	65
D9Mit19	D9Ucla3	1	64
D9Ucla3	D9Ucla5	1	63

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Gria4	Ldlr	5	64	7.812	3.355
Ldlr	D9Mit2	6	61	9.836	3.813
D9Mit2	Pou2f3	3	61	4.918	2.769
Pou2f3	Oaf	1	66	1.515	1.504
Oaf	Drd2	3	63	4.762	2.683
Oaf	Apoa1	3	63	4.762	2.683
Drd2	Apoa1	0	63	0.000	0.000
Drd2	D9Mit27	2	62	3.226	2.244
Drd2	Cryab	2	62	3.226	2.244
Apoa1	D9Mit27	2	62	3.226	2.244
Apoa1	Cryab	2	62	3.226	2.244
D9Mit27	Cryab	0	61	0.000	0.000
D9Mit27	D9Ucla4	4	65	6.154	2.981
Cryab	D9Ucla4	4	65	6.154	2.981
D9Ucla4	Lipc	5	66	7.576	3.257
Lipc	D9Mit8	1	52	1.923	1.904
D9Mit8	D9Ucla6	9	50	18.000	5.433
D9Ucla6	Slc38a3	6	64	9.375	3.644
D9Ucla6	D9Mit36	6	64	9.375	3.644
Slc38a3	D9Mit36	0	50	0.000	0.000
Slc38a3	D9Ucla7	3	50	6.000	3.359
D9Mit36	D9Ucla7	3	50	6.000	3.359
D9Ucla7	D9Mit19	1	66	1.515	1.504
D9Mit19	D9Ucla3	1	65	1.538	1.527
D9Ucla3	D9Ucla5	1	64	1.562	1.550