Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  4
• Reference
  J:34178 Welch CL, et al., Genetic regulation of cholesterol homeostasis: chromosomal organization of candidate genes. J Lipid Res. 1996 Jul;37(7):1406-21
• ID
  MGI:48082

Genes

Gene	Assay Type
D4Mit19	PCR amplified length variant
Coq3	reported elsewhere
D4Mit4	PCR amplified length variant
D4Ucla3	reported elsewhere
D4Mit17	PCR amplified length variant
D4Mit9	PCR amplified length variant
D4Ucla4	reported elsewhere
Scp2	reported elsewhere
D4Ucla5	reported elsewhere
D4Mit16	PCR amplified length variant
D4Mit11	PCR amplified length variant
Fdpsl2	reported elsewhere
Oprd1	reported elsewhere
Rsrp1	reported elsewhere
Eno1	reported elsewhere
Nppa	reported elsewhere
D4Mit14	PCR amplified length variant
Pla2g2a	reported elsewhere
Pla2g2c	reported elsewhere
Pla2g5	reported elsewhere
D4Ucla1	reported elsewhere

Notes

• Reference
  The marker maps experimentally derived in this paper were overlapped with published maps for a number of QTL regions associated with plasma total cholesterol (Chromosomes 1, 5, 6, 7, 12, 15 ,18), plasma HDL cholesterol (Chromosomes 1, 5, 7, 17), plasma LDL/VLDL cholesterol (Chromosomes 9, 12, 13, 15), plasma triglyceride (Chromosomes 5, 7), gallstones (Chromosome 2), and obesity (Chromosomes 4, 6, 7, 9, 12, 15). Authors use Lipc, Brn3.1, Ghrhrr, Gad-1ps, Otf11, Sel1, Tcfcoup2, Crfr, Brn5.0, G6pd, Otf9, Igl1, Pgs1, Lgals1 and Lgals2 for locus symbols Hpl, Pou4f3, Ghrhr, Gad1-ps, Pou2f3, DSell, Aporp1, Crhr, Pou6f1, G6pdx, Pou3f4, Igl-5, Ptgs1, Lgals4 and Lgals6 respectively.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  UCLA (BSB)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D4Mit19	Coq3	5	55
Coq3	D4Mit4	2	55
D4Mit4	D4Ucla3	5	52
D4Ucla3	D4Mit17	5	51
D4Mit17	D4Mit9	5	56
D4Mit9	D4Ucla4	5	60
D4Ucla4	Scp2	7	55
Scp2	D4Ucla5	1	61
D4Ucla5	D4Mit16	2	62
D4Mit16	D4Mit11	1	48
D4Mit16	Fdpsl2	1	48
D4Mit11	Oprd1	2	64
Fdpsl2	Oprd1	2	64
Oprd1	Rsrp1	2	62
Rsrp1	Eno1	2	62
Eno1	Nppa	3	63
Nppa	D4Mit14	2	64
D4Mit14	Pla2g2a	3	60
D4Mit14	Pla2g2c	3	60
D4Mit14	Pla2g5	3	60
Pla2g5	D4Ucla1	1	63
Pla2g2c	D4Ucla1	1	63
Pla2g5	D4Ucla1	1	63

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D4Mit19	Coq3	5	60	8.333	3.568
Coq3	D4Mit4	2	57	3.509	2.437
D4Mit4	D4Ucla3	5	57	8.772	3.747
D4Ucla3	D4Mit17	5	56	8.929	3.811
D4Mit17	D4Mit9	5	61	8.197	3.512
D4Mit9	D4Ucla4	5	65	7.692	3.305
D4Ucla4	Scp2	7	62	11.290	4.019
Scp2	D4Ucla5	1	62	1.613	1.600
D4Ucla5	D4Mit16	2	64	3.125	2.175
D4Mit16	D4Mit11	1	49	2.041	2.020
D4Mit16	Fdpsl2	1	49	2.041	2.020
D4Mit11	Oprd1	2	66	3.030	2.110
Fdpsl2	Oprd1	2	66	3.030	2.110
Oprd1	Rsrp1	2	64	3.125	2.175
Rsrp1	Eno1	2	64	3.125	2.175
Eno1	Nppa	3	66	4.545	2.564
Nppa	D4Mit14	2	66	3.030	2.110
D4Mit14	Pla2g2a	3	63	4.762	2.683
D4Mit14	Pla2g2c	3	63	4.762	2.683
D4Mit14	Pla2g5	3	63	4.762	2.683
Pla2g5	D4Ucla1	1	64	1.562	1.550
Pla2g2c	D4Ucla1	1	64	1.562	1.550
Pla2g5	D4Ucla1	1	64	1.562	1.550