Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  2
• Reference
  J:36996 van Wezel T, et al., Gene interaction and single gene effects in colon tumour susceptibility in mice [see comments]. Nat Genet. 1996 Dec;14(4):468-70
• ID
  MGI:47961

Genes

Gene	Assay Type
Scc2	resistance/susceptibility
D2Mit14a	PCR amplified length variant
Ptprj	resistance/susceptibility

Notes

• Experiment
  QTL analysis of 192 (BALB/c x Ccs-19)F2 mice revealed two colon tumor susceptibility loci, Ptprj and Scc2, linked to D2Mit14a on mouse Chromosome 2. The best linkage is reported between Ptprj and D2MIt14a (P = 0.00004).
  
  Authors suggest Tgfb2, Msh2, Apc and Grl1 as possible candidate genes for Scc2, Scc3, Scc4 and Scc5 respectively.