Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  8
• Reference
  J:36596 Fletcher CF, et al., Absence epilepsy in tottering mutant mice is associated with calcium channel defects. Cell. 1996 Nov 15;87(4):607-17
• ID
  MGI:47622

Genes

Gene	Assay Type	Description
D8Mit102	PCR amplified length variant
D8Mit103	PCR amplified length variant
D8Mit104	PCR amplified length variant
D8Mit235	PCR amplified length variant
D8Mit249	PCR amplified length variant
D8Mit75	PCR amplified length variant
D8Mit77	PCR amplified length variant
D8Mit234	PCR amplified length variant
D8Mit161	PCR amplified length variant
D8Mit247	PCR amplified length variant
D8Mit265	PCR amplified length variant
D8Mit236	PCR amplified length variant
D8Mit237a	PCR amplified length variant
D8Mit238	PCR amplified length variant
D8Mit264	PCR amplified length variant
D8Mit78	PCR amplified length variant
Cacna1a	Southern analysis	Cch1a1 probe1
Lyl1	Southern analysis	Lyl1 cDNA1
Junb	Southern analysis	Junb cDNA1
D8Mit283	PCR amplified length variant
D8Mit79	PCR amplified length variant
D8Mit105	PCR amplified length variant

Notes

• Reference
  Authors state that the mouse tg phenotype is coded by the mouse Chromosome 8 locus Cacna1a.
• Experiment
  The following order of loci was determined in 1100 F2 progeny derived from an intercross between (B6.AKR-tg^la +/+ Os x CAST/Ei)F1-tg^la/+ mice; D8Mit102 - D8Mit103 - D8Mit104 - D8Mit235 - D8Mit249 - D8Mit75 - D8Mit77 - D8Mit234 - D8Mit161 - D8Mit247 -D8Mit265 - D8Mit236 - D8Mit237 - D8Mit238 - D8Mit264 - D8Mit78 - Cacna1a - Lyl1 - Junb - D8Mit283 - D8Mit79 - D8Mit105. In this intercross D8Mit78 was found to be 0.04 +/- 0.05 cM proximal of Cacna1a. In addition Lyl1 was nonrecombinant with Cacna1a in this cross.