Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  1
• Reference
  J:34785 Christner PJ, et al., A high-resolution linkage map of the tight skin 2 (Tsk2) locus: a mouse model for scleroderma (SSc) and other cutaneous fibrotic diseases. Mamm Genome. 1996 Aug;7(8):610-2
• ID
  MGI:47155

Genes

Gene	Assay Type
D1Mit173	PCR amplified length variant
D1Mit233	PCR amplified length variant
Col3a1	visible phenotype
D1Mit174	PCR amplified length variant
D1Mit175	PCR amplified length variant
D1Mit236	PCR amplified length variant
D1Mit248	PCR amplified length variant
D1Mit213	PCR amplified length variant
D1Mit18	PCR amplified length variant

Notes

• Reference
  Authors state that Col3a1 is a likely candidate gene for Tsk2.

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b>/<c> <c> <c> <c> <c> <c> <c> <c> <c>
• Strain
  (B6.101-Col3a1/+ x CAST/Ei)F1
• Male Parent
  <c> <c> <c> <c> <c> <c> <c> <c> <c>/<c> <c> <c> <c> <c> <c> <c> <c> <c>
• Strain
  CAST/EiJ
• Allele 1
  b from C57BL/6
• Allele 2
  c from CAST/EiJ

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
D1Mit173	D1Mit233	1	154
D1Mit233	Col3a1	1	154
D1Mit233	D1Mit174	1	154
D1Mit233	D1Mit175	1	154
D1Mit233	D1Mit236	1	154
D1Mit233	D1Mit248	1	154
Col3a1	D1Mit213	0	155
D1Mit174	D1Mit213	0	155
D1Mit175	D1Mit213	0	155
D1Mit236	D1Mit213	0	155
D1Mit248	D1Mit213	0	155
D1Mit213	D1Mit18	5	150

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D1Mit173	D1Mit233	1	155	0.645	0.643
D1Mit233	Col3a1	1	155	0.645	0.643
D1Mit233	D1Mit174	1	155	0.645	0.643
D1Mit233	D1Mit175	1	155	0.645	0.643
D1Mit233	D1Mit236	1	155	0.645	0.643
D1Mit233	D1Mit248	1	155	0.645	0.643
Col3a1	D1Mit213	0	155	0.000	0.000
D1Mit174	D1Mit213	0	155	0.000	0.000
D1Mit175	D1Mit213	0	155	0.000	0.000
D1Mit236	D1Mit213	0	155	0.000	0.000
D1Mit248	D1Mit213	0	155	0.000	0.000
D1Mit213	D1Mit18	5	155	3.226	1.419