Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  1
• Reference
  J:34785 Christner PJ, et al., A high-resolution linkage map of the tight skin 2 (Tsk2) locus: a mouse model for scleroderma (SSc) and other cutaneous fibrotic diseases. Mamm Genome. 1996 Aug;7(8):610-2
• ID
  MGI:47153

Genes

Gene	Assay Type
D1Mit4	PCR amplified length variant
D1Mit243	PCR amplified length variant
D1Mit173	PCR amplified length variant
D1Mit233	PCR amplified length variant
Col3a1	visible phenotype
D1Mit174	PCR amplified length variant
D1Mit175	PCR amplified length variant
D1Mit236	PCR amplified length variant
D1Mit248	PCR amplified length variant
Col3a1	reported elsewhere
D1Mit213	PCR amplified length variant
D1Mit18	PCR amplified length variant
D1Mit5.1	PCR amplified length variant
Fn1	reported elsewhere
D1Mit7	PCR amplified length variant
Inha	reported elsewhere
Des	reported elsewhere

Notes

• Reference
  Authors state that Col3a1 is a likely candidate gene for Tsk2.

CROSS

• Type
  Backcross, sexes unspecified or combined
• Female Parent
  <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b> <b>/<c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c>
• Strain
  (B6.101-Col3a1/+ x CAST/Ei)F1
• Male Parent
  <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c>/<c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c> <c>
• Strain
  CAST/EiJ
• Allele 1
  b from C57BL/6
• Allele 2
  c from CAST/EiJ

CROSS Data

MC #mice	D1Mit4	D1Mit243	D1Mit173	D1Mit233	Col3a1	D1Mit174	D1Mit175	D1Mit236	D1Mit248	Col3a1	D1Mit213	D1Mit18	D1Mit5.1	Fn1	D1Mit7	Inha	Des
89	b	b	b	b	b	b	b	b	b	.	b	b	b	.	b	.	.
4	c	b	b	b	b	b	b	b	b	.	b	b	b	.	b	.	.
8	c	c	b	b	b	b	b	b	b	.	b	b	b	.	b	.	.
2	c	c	c	b	b	b	b	b	b	b	b	b	b	.	b	.	.
2	c	c	c	c	b	b	b	b	b	b	b	b	b	.	b	.	.
1	b	b	b	b	b	b	b	b	b	b	c	c	c	c	c	c	c
5	b	b	b	b	b	b	b	b	b	b	b	c	c	c	c	c	c
1	b	b	b	b	b	b	b	b	b	b	b	b	c	c	c	c	c
3	b	b	b	b	b	b	b	b	b	b	b	b	b	b	b	c	c

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D1Mit4	D1Mit243	4	115	3.478	1.709
D1Mit243	D1Mit173	8	115	6.957	2.372
D1Mit173	D1Mit233	2	115	1.739	1.219
D1Mit233	Col3a1	2	115	1.739	1.219
Col3a1	D1Mit174	0	115	0.000	0.000
D1Mit174	D1Mit175	0	115	0.000	0.000
D1Mit175	D1Mit236	0	115	0.000	0.000
D1Mit236	D1Mit248	0	115	0.000	0.000
D1Mit213	D1Mit18	5	115	4.348	1.902
D1Mit18	D1Mit5.1	1	115	0.870	0.866