Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  17
• Reference
  J:30574 Fritz RB, et al., Major histocompatibility complex-linked control of the murine immune response to myelin basic protein. J Immunol. 1985 Apr;134(4):2328-32
• ID
  MGI:46321

Genes

Gene	Assay Type
H2-I	immunological
Eae1	resistance/susceptibility

Notes

• Experiment
  Congenic Intra H2 recombinant strains of mice were analyzed for susceptibility to experimental allergic encephalomyelitis as determined by the response to myelin basic protein (MBP). C57BL/10J, A/SW and B10.Y(6R) mice are resistant to MBP whereas B10.A and B10.PL are highly susceptible. The experiments indicated that control of the response to MBP is controlled by a region of mouse Chromosome 17 (Eae1) within the H2-I locus.