Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  16
• Reference
  J:31897 Fan CM, et al., Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Mol Cell Neurosci. 1996 Jan;7(1):1-16
• ID
  MGI:46248

Genes

Gene	Assay Type	Description
App	reported elsewhere
Tiam1	reported elsewhere
Sim2	Southern analysis	Sim2 cDNA1

Notes

• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b>/<s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b>/<b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	App	Tiam1	Sim2
95	b	b	b
70	s	s	s
3	s	b	b
2	b	s	s
2	s	s	b
3	b	b	s
0	s	s	s
0	b	b	b
3	s	s	s
2	b	b	b

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
App	Tiam1	0	7
Tiam1	Sim2	0	10

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
App	Tiam1	5	187	2.674	1.180
Tiam1	Sim2	5	190	2.632	1.161