Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  11
• Reference
  J:31335 Greco TL, et al., Analysis of the vestigial tail mutation demonstrates that Wnt-3a gene dosage regulates mouse axial development. Genes Dev. 1996 Feb 1;10(3):313-24
• ID
  MGI:46159

Genes

Gene	Allele	Assay Type
D11Mit1		PCR amplified length variant
Egfr	Egfr^wa2	visible phenotype
D11Mit22		PCR amplified length variant
Csf2		PCR amplified length variant
Wnt3a		visible phenotype
D11Mit5		PCR amplified length variant

Notes

• Reference
  Authors suggest Wnt3a may be responsible for the vt mutation.
• Experiment
  67 progeny from a (VT vt/vt x CASA/Rk)F1 x VT vt/vt backcross were scored for vt and wa2 and typed for markers on the proximal half of mouse Chromosome 11. The following gene order and genetic distances were obtained. D11Mit1 - 15 cM - Egfr - 19 cM - D11Mit22 - 3.6 cM - Csfgm - 3.5 cM - vt - 2.2 cM - D11Mit5.