Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  X
• Reference
  J:9551 Nagamine CM, et al., Chromosome mapping and expression of a putative testis-determining gene in mouse. Science. 1989 Jan 6;243(4887):80-3
• ID
  MGI:45881

Genes

Gene	Assay Type	Description
Zfx	Southern analysis	mYfin
Xic	reported elsewhere
Pgk1	reported elsewhere
Gla	reported elsewhere
T(X;16)16H	visible phenotype
T(X;7)6Rl	visible phenotype

Notes

• Experiment
  A probe derived from the mouse Y Chromosome hybridized to sequences on the X Chromosome. One of these sequences identified by a HindIII fragment of 3.6kb (Zfx) hybridized more intensely when two mouse X-Chromosomes were present. Chinese hamster with mouse hybrids were used to confirm an X location for Zfx. Hybrids VI-6 carries a complete X Chromosome, B20c12 carries a partial X from T(X;16)16H and N15 has a partial X from T(X;7)6Rl. The mYfin probe hybridized too the 3.6kb fragment from VI-6 and N15 but not B10c12 indicating that Zfx maps to a region identified by the T(X;16)16H and T(X;7)6Rl breakpoints. This region contains genes Xce, Pgk1 and Ags.