Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  7
• Reference
  J:27740 Palmer S, et al., A contravention of Ohno's law in mice [see comments]. Nat Genet. 1995 Aug;10(4):472-6
• ID
  MGI:45572

Genes

Gene	Assay Type	Description
Prkcg	reported elsewhere
Clcn4	PCR amplified length variant	Clc4-pA, Clc4-pB
D7Nds5	reported elsewhere

Notes

• Reference
  Authors use Clcn4 for locus symbols Clc4-1 and Clc4-2 respectively.
• Experiment
  Male backcross mice from the EUCIB BSS panel that received a distal X Chromosome from C57BL/6 and a proximal Chromosome 7 from M. spretus do not carry a chloride channel 4 gene. This result supports the premise that Clc4-2 maps to Chromosome 7 in C57BL/6. The missing data is a consequence of the fact that M. spretus mice do not have a chloride channel 4 gene on Chromosome 7. The chloride channel gene Clc4-1 maps to the X Chromosome in M. spretus.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b>/<s> <s> <s>
• Strain
  (C57BL/6J x SPR or SEG/Pas)F1
• Male Parent
  <s> <s> <s>/<s> <s> <s>
• Strain
  SPR or SEG/Pas
• Mapping Panel
  EUCIB (BSS)
• Allele 1
  b from C57BL/6J
• Allele 2
  s from SPR or SEG/Pas

CROSS Data

MC #mice	Prkcg	Clcn4	D7Nds5
20	b	b	b
20	s	.	s
2	s	b	b
1	b	.	s
4	s	.	b
4	b	b	s

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Prkcg	Clcn4	2	26	7.692	5.226
Clcn4	D7Nds5	4	26	15.385	7.076