Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  11
• Reference
  J:25562 Reiner O, et al., Lissencephaly gene (LIS1) expression in the CNS suggests a role in neuronal migration. J Neurosci. 1995 May;15(5 Pt 2):3730-8
• ID
  MGI:45221

Genes

Gene	Assay Type	Description
Myhs	Southern analysis	p32
Chrnb1	Southern analysis	pAchrb
Pafah1b1	Southern analysis	LIS-ORF
D11Mit7	PCR amplified length variant	M119
Evi2a	Southern analysis	pBK4

Notes

• Reference
  Authors use Lis1, Lis3, Lis4 and Evi2a for the locus symbols Mdsh, Mdsh3, Mdsh4 and Evi2 respectively.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <a> <a> <a> <a> <a>/<s> <s> <s> <s> <s>
• Strain
  (AEJ/Gn-a Gdf5/a Gdf5 x M. spretus)F1
• Male Parent
  <a> <a> <a> <a> <a>/<a> <a> <a> <a> <a>
• Strain
  AEJ/Gn-a Gdf5
• Allele 1
  a from AEJ/Gn-a Gdf5
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Myhs	Chrnb1	Pafah1b1	D11Mit7	Evi2a
99	a	a	a	a	a
87	s	s	s	s	s
2	a	s	s	s	s
3	s	a	a	a	a
1	s	s	a	a	a
1	s	s	s	a	a
1	a	a	a	a	s

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Myhs	Chrnb1	5	194	2.577	1.138
Chrnb1	Pafah1b1	1	194	0.515	0.514
Pafah1b1	D11Mit7	1	194	0.515	0.514
D11Mit7	Evi2a	1	194	0.515	0.514