Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  17
• Reference
  J:22127 Fishel R, et al., The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer [published erratum appears in Cell 1994 Apr 8;77(1):167]. Cell. 1993 Dec 3;75(5):1027-38
• ID
  MGI:44366

Genes

Gene	Assay Type	Description
Eif2ak2	Southern analysis	Tik cDNA1
Sos1	reported elsewhere
Msh2	Southern analysis	Msh2 cDNA1
Lhcgr	Southern analysis	Lhcgr cDNA2

Notes

• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b>/<s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b>/<b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Eif2ak2	Sos1	Msh2	Lhcgr
68	b	b	b	b
87	s	s	s	s
1	s	b	b	b
0	b	s	s	s
1	s	s	b	b
1	b	b	s	s
0	s	s	s	b
1	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Eif2ak2	Sos1	0	3
Sos1	Msh2	1	1
Msh2	Lhcgr	0	32

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Eif2ak2	Sos1	1	162	0.617	0.615
Sos1	Msh2	3	161	1.863	1.066
Msh2	Lhcgr	1	191	0.524	0.522