Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  2
• Reference
  J:18309 Hess EJ, et al., Deletion map of the coloboma (Cm) locus on mouse chromosome 2. Genomics. 1994 May 1;21(1):257-61
• ID
  MGI:43710

Genes

Gene	Assay Type	Description
Bmp2	reported elsewhere
Plcb1	Southern analysis	Plcb cDNA1
Snap25	Southern analysis	pSNAP8.52
Pcsk2	Southern analysis	mPC2

Notes

• Reference
  The authors use Bmp-2a, Plcb-1 and Nec-2 for Bmp2, Plcb and Pcsk2 respectively. This study identifies two genes, Plcb and Snap, that may be considered candidate genes for Cm.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b>/<s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b>/<b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

2x2 Data Reported

Marker 1	Marker 2	# Recombinants	# Parentals
Bmp2	Plcb1	3	175
Plcb1	Snap25	1	179
Snap25	Pcsk2	4	171

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Bmp2	Plcb1	3	178	1.685	0.965
Plcb1	Snap25	1	180	0.556	0.554
Snap25	Pcsk2	4	175	2.286	1.130