Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  X
• Reference
  J:17492 Levinson B, et al., The mottled gene is the mouse homologue of the Menkes disease gene [see comments]. Nat Genet. 1994 Apr;6(4):369-73
• ID
  MGI:43604

Genes

Gene	Allele	Assay Type	Description
Atp7a	Atp7a^Mo	restriction analysis	Mo cDNA
Pgk1		restriction analysis	C15.F1, C96.G2

Notes

• Reference
  Authors state the Mo mouse is the murine model for Menkes disease. The candidate gene for mottled is Atp7a.
• Experiment
  Two previously identified YAC clones which carry the Pgk1 gene were tested. All the restriction fragments detected by the Mo cDNA probe in genomic DNA were also present in the two YAC clones. This indicates that the Atp7a gene is located at the Mo locus site and is linked to Pgk1.