Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  11
• Reference
  J:18190 Chen XS, et al., cDNA cloning, expression, mutagenesis of C-terminal isoleucine, genomic structure, and chromosomal localizations of murine 12-lipoxygenases. J Biol Chem. 1994 May 13;269(19):13979-87
• ID
  MGI:43422

Genes

Gene	Assay Type	Description
Myhs	reported elsewhere
Alox12	Southern analysis	Alox12p cDNA1
Alox12e	Southern analysis	Alox12-ps1 genomic1
Alox15	Southern analysis	Alox12l cDNA1
Evi2a	reported elsewhere
Mpo	reported elsewhere

Notes

• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Myhs	Alox12	Alox12e	Alox15	Evi2a	Mpo
38	b	b	b	b	b	b
38	s	s	s	s	s	s
1	s	b	b	b	b	b
2	b	s	s	s	s	s
0	s	s	b	b	b	b
0	b	b	s	s	s	s
0	s	s	s	b	b	b
0	b	b	b	s	s	s
2	s	s	s	s	b	b
2	b	b	b	b	s	s
2	s	s	s	s	s	b
4	b	b	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Myhs	Alox12	0	6
Alox12	Alox12e	0	53
Alox12e	Alox15	0	102
Alox15	Evi2a	0	43
Evi2a	Mpo	2	51

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Myhs	Alox12	3	95	3.158	1.794
Alox12	Alox12e	0	142	0.000	0.000
Alox12e	Alox15	0	191	0.000	0.000
Alox15	Evi2a	4	132	3.030	1.492
Evi2a	Mpo	8	142	5.634	1.935