Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  10
• Reference
  J:13549 Collins AC, et al., Growth quantitative trait loci (QTL) on mouse chromosome 10 in a Quackenbush-Swiss x C57BL/6J backcross. Mamm Genome. 1993;4(8):454-8
• ID
  MGI:42387

Genes

Gene	Assay Type	Description
Igf1	visible phenotype
D10Mit12	PCR amplified length variant	M172
D10Mit14	PCR amplified length variant	M175

Notes

• Experiment
  Analysis of variance was used to indicate a significant association of litter size (p = .058) and body weight variation (p = .019) with the D10Mit12 locus, and of body variation (p = .009) with D10Mit14. Data were obtained from backcross mice derived from (Quackenbush-Swiss (QS) x C57BL/6J)F1 x C57BL/6J matings. All types of reciprocal crosses were made in which the C57BL/6J strain contributed 3/4 of the gene pool. The D10Mit12 and D10Mit14 loci were selected for analysis because of their proximity to Igf1. Igf1 is a candidate gene for a growth and litter size quantitative trait locus( QTL). Linkage distance between D10Mit12 and D10Mit14 on Chromosome 10 was estimated at 27.5 cM.