Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  7
• Reference
  J:4586 Bianchi AB, et al., Reassignment of the H-ras-1 gene to the Hbb-terminus region of mouse chromosome 7. Mamm Genome. 1993;4(4):220-2
• ID
  MGI:41899

Genes

Gene	Assay Type	Description
Oca2	visible phenotype
Hras1-ps1	Southern analysis	HB-11
Igf1r	Southern analysis	pIGF-I-R.8
Hbb	Southern analysis	pPK268
Prkcb	Southern analysis	Pkc(beta)-PCR
Hras	Southern analysis	H-ras-Int1
Fgf3	Southern analysis	Int-2 cDNA

Notes

• Reference
  Authors use Int-2 for Fgf3. Authors state that previously defined Hras1 gene is Hras1-ps1 and is located proximal to Hbb.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <m> <m> <m> <m> <m> <m> <m>/<s> <s> <s> <s> <s> <s> <s>
• Strain
  (129/Rl-Oca2

  Tyr x M. spretus)F1

• Male Parent
  <m> <m> <m> <m> <m> <m> <m>/<m> <m> <m> <m> <m> <m> <m>
• Strain
  129/Rl-Oca2

  Tyr

• Allele 1
  m from 129/Rl
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Oca2	Hras1-ps1	Igf1r	Hbb	Prkcb	Hras	Fgf3
43	m	m	m	m	m	m	m
48	s	s	s	s	s	s	s
3	m	s	s	s	s	s	s
2	s	m	m	m	m	m	m
1	m	m	s	s	s	s	s
1	s	s	m	m	m	m	m
18	m	m	m	s	s	s	s
8	s	s	s	m	m	m	m
14	m	m	m	m	s	s	s
9	s	s	s	s	m	m	m
12	m	m	m	m	m	s	s
16	s	s	s	s	s	m	m
1	m	m	m	m	m	m	s
0	s	s	s	s	s	s	m
1	m	s	s	s	m	m	m
1	s	m	m	m	s	s	s
1	m	m	s	s	s	m	m
1	s	s	s	m	s	s	s
2	s	m	m	m	m	s	s
1	s	m	m	s	m	m	s

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Oca2	Hras1-ps1	10	183	5.464	1.680
Hras1-ps1	Igf1r	3	183	1.639	0.939
Igf1r	Hbb	28	183	15.301	2.661
Hbb	Prkcb	27	183	14.754	2.622
Prkcb	Hras	31	183	16.940	2.773
Hras	Fgf3	2	183	1.093	0.769