Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  2
• Reference
  J:2185 White RA, et al., The murine pallid mutation is a platelet storage pool disease associated with the protein 4.2 (pallidin) gene. Nat Genet. 1992 Sep;2(1):80-3
• ID
  MGI:41252

Genes

Gene	Allele	Assay Type	Description
Bloc1s6	Bloc1s6^pa	visible phenotype
Epb42		Southern analysis	Epb4.2 cDNA

Notes

• Reference
  The pallid (pa) mutation is associated with the Epb4.2 protein.
• Experiment
  The visible recessive mutation pallid (pa) is suggested to be a mutation in the Epb4.2 gene. The RFLP patterns for C57BL/6J and C57BL/6J-pa/pa, a congenic strain backcrossed for 45 generations, were substantially different. Further, Northern analysis indicated smaller transcripts of Epb4.2 in pa/pa kidney and skin when compared to +/+. Normal size Epb4.2 transcripts were found in pa/pa brain, heart, and liver.