Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  15
• Reference
  J:10942 Davisson MT, et al., The hairy ears (Eh) mutation is closely associated with a chromosomal rearrangement in mouse chromosome 15. Genet Res. 1990 Oct-Dec;56(2-3):167-78
• ID
  MGI:41158

Genes

Gene	Assay Type
Slc45a2	visible phenotype
Gpd1	electrophoretic
Adamts20	visible phenotype
Eh	visible phenotype

Notes

• Reference
  A Chromosome 15 linkage stock was created by crossing B6-uw Gpt1^a bt^2J Gdc1^b to NZB/BlNJ Gpt1^b Gdc1^b. An F2 from this cross was mated to CASA/Rk Gpt1^b Gdc1^d. The marker stock was maintained by inbreeding and selecting homozygous uw bt^2J Gdc1^d Gpt1^b offspring. Mice from this marker stock were crossed to B6-Eh/+ and the F1 mice backcrossed to the marker stock to test for linkage. Linkage was also analyzed from crosses made from mice doubly heterozygous for Eh and In(15)Rk outcrossed to C57BL/6JEi. All parental strains listed here as derived, all allele symbols listed here were as published in the reference and visible phenotypes identified as + for wild type or as expressed with the proper gene symbol.

CROSS

• Type
  Backcross, male
• Female Parent
  uw <b> bt +/uw <b> bt +
• Strain
  STOCK Slc45a2 Gpt Gpd1 Adamts20/J
• Male Parent
  uw <d> bt +/+ <b> + Eh
• Strain
  (STOCK Slc45a2 Gpt Adamts20 x C57BL/6JEi-Eh/+)F1

CROSS Data

MC #mice	Slc45a2	Gpd1	Adamts20	Eh
4	uw	d	bt	+
7	+	b	+	Eh
3	uw	b	+	Eh
3	+	d	bt	+
0	uw	d	+	Eh
0	+	b	bt	+
0	uw	d	bt	Eh
1	uw	d	+	+

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Slc45a2	Gpd1	6	18	33.333	11.111
Gpd1	Adamts20	1	18	5.556	5.399
Adamts20	Eh	1	18	5.556	5.399