Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  2
• Reference
  J:44 Moen CJ, et al., Scc-1, a novel colon cancer susceptibility gene in the mouse: linkage to CD44 (Ly-24, Pgp-1) on chromosome 2. Oncogene. 1992 Mar;7(3):563-6
• ID
  MGI:41041

Genes

Gene	Assay Type	Description
Hc	Southern analysis	pMC5.04
Cd44	immunological	Ly-24.2 monoclonal antibody
Ptprj	visible phenotype	DMH-induced tumor
Fshb	Southern analysis	FSHB1.4
B2m	Southern analysis	pB2-m2

Notes

• Experiment
  Analysis of variance indicated a Chromosome 2 linkage of Scc1 with Cd44 (p = 0.0001) in BALB/cJ x (BALB/cJ x CcS-19)F1 backcross mice. CcS-19 is a recombinant congenic strain derived between background BALB/cHeA and donor STS/A. Linkage of Ptprj with Fshb(p = 0.003), B2m (p = 0.024) and Hc (p = 0.04) was also observed.