Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  15
• Reference
  J:3132 Barker CS, et al., Activation of the prolactin receptor gene by promoter insertion in a Moloney murine leukemia virus-induced rat thymoma. J Virol. 1992 Nov;66(11):6763-8
• ID
  MGI:40964

Genes

Gene	Assay Type	Description
Ghr	Southern analysis	Ghr genomic
Mlvi2	Southern analysis	pTS6
Prlr	Southern analysis	Prlr probe
D15Fcr1	reported elsewhere	Brannan, et al., Genomics 1992
Myc	reported elsewhere	Brannan, et al., Genomics 1992

Notes

• Reference
  The lack of recombination between Ghr and Mlvi-2 and between Mlvi-2 and Prlr suggest they are < 1.5 cM and < 1.6 cM apart, respectively.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Ghr	Mlvi2	Prlr	D15Fcr1	Myc
44	b	b	b	b	b
59	s	s	s	s	s
0	s	b	b	b	b
0	b	s	s	s	s
0	s	s	b	b	b
0	b	b	s	s	s
8	s	s	s	b	b
7	b	b	b	s	s
12	s	s	s	s	b
18	b	b	b	b	s

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Ghr	Mlvi2	0	46
Mlvi2	Prlr	0	40
Prlr	D15Fcr1	2	7
D15Fcr1	Myc	3	9

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Ghr	Mlvi2	0	194	0.000	0.000
Mlvi2	Prlr	0	188	0.000	0.000
Prlr	D15Fcr1	17	157	10.828	2.480
D15Fcr1	Myc	33	160	20.625	3.199