Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  6
• Reference
  J:11207 Goodwin RG, et al., Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor. Mol Cell Biol. 1991 Jun;11(6):3020-6
• ID
  MGI:39992

Genes

Gene	Assay Type	Description
Raf1	reported elsewhere	de Lapeyriere O., Oncogene 5:823-831, 1990
Tnfrsf1a	Southern analysis	TNFR-1 cDNA
Cd4	Southern analysis	Ly-4 cDNA
Fgf6	reported elsewhere	de Lapeyriere O., Oncogene 5:823-831, 1990

Notes

• Reference
  Revised gene symbols: Nppa and Cd4 (formerly Anf and Ly-4 respectively). Numbering for Tnfr genes Tnfr1 (Chromosome 6) and Tnfr2 (Chromosome 4) has been revised to conform to human nomenclature.

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b>/<s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b>/<b> <b> <b> <b>
• Strain
  C57BL/6J
• Mapping Panel
  Copeland-Jenkins
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Raf1	Tnfrsf1a	Cd4	Fgf6
72	b	b	b	b
74	s	s	s	s
5	b	s	s	s
1	s	b	b	b
0	b	b	s	s
0	s	s	b	b
2	b	b	b	s
1	s	s	s	b

Additional Mice Typed Only for Specific Pairs of Loci

Marker 1	Marker 2	# Recombinants	# Parentals
Raf1	Tnfrsf1a	0	7
Tnfrsf1a	Cd4	0	17
Cd4	Fgf6	0	30

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Raf1	Tnfrsf1a	6	162	3.704	1.484
Tnfrsf1a	Cd4	0	172	0.000	0.000
Cd4	Fgf6	3	185	1.622	0.929