Mapping Data

Experiment

• Experiment
  TEXT
• Chromosome
  7
• Reference
  J:9935 Peters G, et al., The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors. Proc Natl Acad Sci U S A. 1989 Aug;86(15):5678-82
• ID
  MGI:39672

Genes

Gene	Assay Type	Description
Fgf3	Southern analysis	probe j
Fgf4	Southern analysis	.79 human hst genomic

Notes

• Reference
  Revised gene symbols: Fgf3 and Fgf-4 (formerly Int-2 and Hstf-1 respectively).
• Experiment
  Spontaneous mouse tumor S30, derived from the BR6 mouse strain yielded a new 17.5kb Kpn I fragment (using probe j) that was consistent with an insertion of proviral MMTV downstream of Fgf3. Linkage of human Fgf3 with hst was suggestive that this site maybe homologous with hst. The distance between two coding exons of Fgf3 and Fgf-4 is approximately 20kb on COS 16 as measured from the text figure.