Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  16
• Reference
  J:9328 Cheng SV, et al., Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6032-6
• ID
  MGI:39636

Genes

Gene	Assay Type	Description
D16H21S16	Southern analysis	human pGSE9
D16H21S52	Southern analysis	human 511-1H/511-2P
App	Southern analysis	human FB68L and HL124
Sod1	Southern analysis	human pSG1-10
Il10rb	Southern analysis	human 524-5P
Ets2	Southern analysis	human H33

Notes

• Experiment
  Five of the 58 mice included in these data were not typed for D16H21S58. Of these, 4 were non-recombinant for all other markers and 1 was a recombinant between App and Sod1.Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <b> <b> <b> <b> <b> <b>/<s> <s> <s> <s> <s> <s>
• Strain
  (C57BL/6J x M. spretus)F1
• Male Parent
  <b> <b> <b> <b> <b> <b>/<b> <b> <b> <b> <b> <b>
• Strain
  C57BL/6J
• Allele 1
  b from C57BL/6J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	D16H21S16	D16H21S52	App	Sod1	Il10rb	Ets2
23	b	b	b	b	b	b
36	s	s	s	s	s	s
1	s	s	s	b	b	b
2	b	b	b	s	s	s
0	b	b	b	b	b	s
1	s	s	s	s	s	b

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
D16H21S16	D16H21S52	0	63	0.000	0.000
D16H21S52	App	0	63	0.000	0.000
App	Sod1	3	63	4.762	2.683
Sod1	Il10rb	0	63	0.000	0.000
Il10rb	Ets2	1	63	1.587	1.575