Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  4
• Reference
  J:130782 Cheli Y, et al., The Modifier of hemostasis (Mh) locus on chromosome 4 controls in vivo hemostasis of Gp6-/- mice. Blood. 2008 Feb 1;111(3):1266-73
• ID
  MGI:3773658

Genes

Gene
Mh

Notes

• Experiment
  A targeted disruption of Gp6 in mice resulted in a measurable difference in tail bleeding times in Gp6 -/- mice. The locus responsible for the difference was mapped to mouse Chromosome 4 and symbolized as Mh (modifier of hemostasis). Single nucleotide polymorphisms (SNP) were identified in 8 inbred mouse strains including C57BL/6J and 129X1/SvJ. The most significant association of the phenotype was found with SNP rs13477745 LOD 6.9 (p<.001) at bp position 64,020,437 ( v37 assembly) in mouse Chromosome 4.