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Mapping Data
Experiment
  • Experiment
    HYBRID
  • Chromosome
    2
  • Reference
    J:6910 Goff SP, et al., Chromosomal assignment of the endogenous proto-oncogene C-abl. Science. 1982 Dec 24;218(4579):1317-9
  • ID
    MGI:37312
Genes
GeneAlleleAssay TypeDescription
Abl1 Southern analysis pAB3sub3
Notes
  • Experiment
    Somatic cell hybrids were from fusions of Chinese hamster E36 cells and peritoneal macrophages from A/HeJ mice. Genomic DNA was digested with HindIII or XbaI and hybridized on Southern blots using the v-abl DNA probe pAB3sub3. Because this analysis indicated that Chromosome 2 or 19 could carry Abl, one of the hybrids (MACH2A2) was subcloned and analyzed further. Of 3 Abl positive subclones, all retained Chromosome 2. In 1 Abl negative subclone (H3) Chromosome 2 was absent, but Chromsome 19 retained, thusassigning Abl to Chromosome 2.
HYBRID
  • Concordance
    chromosomes
HYBRID Data
Chromosome +/+ +/- -/+ -/-
1 4 0 3 4
2 7 0 0 4
3 3 0 4 4
4 2 0 5 4
5 2 0 5 4
6 3 0 4 4
7 5 0 2 4
8 4 0 3 4
9 3 0 4 4
10 3 0 4 4
11 0 0 7 4
12 7 1 0 3
13 5 0 2 4
14 4 1 3 3
15 7 1 0 3
16 6 1 1 3
17 7 1 0 3
18 5 0 2 4
19 7 0 0 4
X 3 2 4 2
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory