Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  17
• Reference
  J:5011 Lilly F, The inheritance of susceptibility to the Gross leukemia virus in mice. Genetics. 1966 Mar;53(3):529-39
• ID
  MGI:3617636

Genes

Gene	Assay Type
Rgv1	resistance/susceptibility
H2	reported elsewhere
C4b	reported elsewhere

Notes

• Experiment
  Resistance to Gross leukemia virus mapped to mouse Chromosome 17 near the H2 locus (23 cM) in a (C3Hf/Bi x C57BL/6)F2 intercross population. This locus is named Rgv1 (resistance to Gross virus 1). Parental strain C3Hf/Bi carries the k allele at H2 and issusceptible to Gross virus whereas parental strain C57BL/6 carries the b allele at H2 and is highly resistant. Resistance to Gross virus at Rgv1 appears to be dominantly inherited from the C57BL/6 strain. C4b, which maps to 18.8 cM, is a potential candidate gene for Rgv1. A second unlinked locus named Rgv2 is thought to segregate in the F2 population.