Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  9
• Reference
  J:103841 Stylianou IM, et al., Quantitative trait locus analysis for obesity reveals multiple networks of interacting loci. Mamm Genome. 2006 Jan;17(1):22-36
• ID
  MGI:3615282

Genes

Gene	Assay Type
Adip14	visible phenotype
D9Mit15	PCR amplified length variant

Notes

• Experiment
  Linkage analysis was performed on 513 animals from a (SM/J x NZB/BlNJ)F2 intercross to identify QTL affecting obesity traits. Animals were placed on an atherogenic diet for 16 weeks before phenotyping. Parental strain SM/J exhibits smaller body size but higher adiposity compared to parental strain NZB/BlNJ.
  
  Adip14 maps to 60 cM on mouse Chromosome 9 near D9Mit15 (LOD=3.9) with a 95% confidence interval spanning 48 cM - 60 cM. Adip14 exhibits overdominance as heterozygous animals exhibit increased retroperitoneal fat pad weights compared to SM/J or NZB/BlNJ homozygotes. Previously identified adiposity QTL Adip5 (42 cM) maps near the Adip14 interval.