Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  2
• Reference
  J:95958 Mannan AU, et al., Mutation in the gene encoding lysosomal acid phosphatase (Acp2) causes cerebellum and skin malformation in mouse. Neurogenetics. 2004 Dec;5(4):229-38
• ID
  MGI:3574357

Genes

Gene
D2Mit158
D2Mit98
Acp2
D2Mit140
D2Mit100

Notes

• Experiment
  129X1/SvJ X C57BL/6J (218 meioses) and 129X1/SvJ x DBA/2J (208 meioses) were informative in mapping the nax (delayed hair appearance and ataxia) mutation to mouse Chromosome 2, bounded by D2Mit158 and D2Mit100. More refined analysis show nax flanked by D2Mit98 and D2Mit140. The authors used molecular evidence to show that nax was mutated in Acp2.