Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  12
• Reference
  J:94352 Volkman SK, et al., Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J Bone Miner Res. 2003 Aug;18(8):1497-505
• ID
  MGI:3512970

Genes

Gene	Assay Type
Fmgty10	visible phenotype
D12Mit167	PCR amplified length variant

Notes

• Experiment
  487 animals from a heterogeneous stock designated UM-HET3 were analyzed for bone (femur) geometry traits. UM-HET3 is derived from a cross between (BALB/cJ x C57BL/6J)F1 x (C3H/HeJ x DBA/2J)F1. 99 polymorphic markers at an average spacing of 15 cM - 20 cM were used in the genome scan. Nine geometric traits were evaluated for each femur.
  
  Linkage to standard deviation of outer fiber length (StdOFL) and shape factor (SF) mapped to 52 cM on mouse Chromosome 12 near D12Mit167. This locus is designated Fmgty10. C57BL/6J-derived alleles confer increased StdOFL compared to BALB/cJ-derived alleles, and BALB/cJ-derived alleles confer increased SF compared to C57BL/6J-derived alleles.