Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  11
• Reference
  J:94352 Volkman SK, et al., Quantitative trait loci for femoral size and shape in a genetically heterogeneous mouse population. J Bone Miner Res. 2003 Aug;18(8):1497-505
• ID
  MGI:3512969

Genes

Gene	Assay Type
Fmgty9	visible phenotype
D11Mit83	PCR amplified length variant

Notes

• Experiment
  487 animals from a heterogeneous stock designated UM-HET3 were analyzed for bone (femur) geometry traits. UM-HET3 is derived from a cross between (BALB/cJ x C57BL/6J)F1 x (C3H/HeJ x DBA/2J)F1. 99 polymorphic markers at an average spacing of 15 cM - 20 cM were used in the genome scan. Nine geometric traits were evaluated for each femur.
  
  Linkage to cortical thickness, minimum outer fiber length (MinOFL), average outer fiber length (AveOFL), shape factor (SF), and medial/lateral axis bending moment of inertia (Iml) map to 16 cM on mouse Chromosome 11 near D11Mit83. This locus is designated Fmgty9. C57BL/6J-derived alleles confer increased SF, Iml, AveOFL, and MinOFL compared to BALB/cJ-derived alleles. C3H/HeJ-derived alleles confer increased cortical thickness compared to DBA/2J-derived alleles.