Mapping Data

Experiment

• Experiment
  TEXT-Genetic Cross
• Chromosome
  7
• Reference
  J:85400 Johnson KR, et al., Mouse models of USH1C and DFNB18: phenotypic and molecular analyses of two new spontaneous mutations of the Ush1c gene. Hum Mol Genet. 2003 Dec 1;12(23):3075-86
• ID
  MGI:3042159

Genes

Gene	Allele	Assay Type
Ush1c	Ush1c^dfcr-2J	visible phenotype
D7Mit157		PCR
D7Mit272		PCR
D7Mit158		PCR
D7Mit228		PCR
D7Mit145		PCR
D7Mit229		PCR
D7Mit69		PCR
D7Mit239		PCR

Notes

• Experiment
  Using linkage intercrosses of the dfcr mutants with CAST/Ei, the authors mapped the dfcr and dfcr-2J mutations to mouse Chromosome 7. Haplotype analysis using 54 F2 mice (108 meioses) positioned dfcr between D7Mit157 (3.7% recombination) and D7Mit272 (1.9% recombination) . Further analysis of 93 F2 mice (186 meioses) placed the dfcr- 2J mutation between D7Mit228 (4.8% recombination) and D7Mit145 (5.4% recombination), Dfcr-2J was non-recombinant with markers D7Mit229, D7Mit69 and D7Mit230 whereas dfcr was non-recombinant with D7Mit158.