Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  15
• Reference
  J:76126 Workman MS, et al., Analysis of quantitative trait locus effects on the size and shape of mandibular molars in mice. Genetics. 2002 Apr;160(4):1573-86
• ID
  MGI:2386726

Genes

Gene	Assay Type
Tshp15	visible phenotype
D15Mit13
Tshp16	visible phenotype
D15Mit5

Notes

• Experiment
  76 polymorphic microsatellite markers at an average distance of 27.5 cM were screened in 535 (SM/J x LG/J)F2 animals to identify QTLs associated with tooth development. Parental inbred strain LG/J exhibits larger body size compared to SM/J. Tshp15 and Tshp16, QTLs influencing tooth shape, mapped to mouse Chromosome 15. The Tshp15 interval spans 6.7 cM - 46.9 cM and the Tshp16 interval spans 22.2 cM - 46.9 cM on chromosome 15. Tshp15 and Tshp16 exceed the P<0.001 significance threshold of LOD=4.185.