Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  1
• Reference
  J:70423 Eggenschwiler JT, et al., Rab23 is an essential negative regulator of the mouse Sonic hedgehog signalling pathway. Nature. 2001 Jul 12;412(6843):194-8
• ID
  MGI:2137903

Genes

Gene	Assay Type
D1Mit319	overlapping clones
13.MMHAP88FRE7.seq	overlapping clones
D1Mit411	overlapping clones
Prim2	overlapping clones
Rab23	overlapping clones
D1Mit318	overlapping clones
Zfp451	overlapping clones
30.MHAa96c6.seq	overlapping clones
D1Mit243	overlapping clones

Notes

• Experiment
  The authors used a genetic map to narrow the opb2 mutation to a 0.3 cM region on Chromosome 1. This interval was represented by overlapping YACs and three characterized genes were identified in it. Subsequent sequence analysis identified mutations in theRab23 gene in the opb1 and opb2 mutants that introduced early stop codons into the ORFs. The order of markers in this region was determined to be: D1Mit319 - 13.MMHAP88Fre7.seq - D1Mit411 - 3' - Prim2 - 5' - 5'- Rab23 - 3' - D1Mit318 - 3'- Kiaa0576-hp - 5' - 30.MHAa96c6.seq - D1Mit243.