About   Help   FAQ
Mapping Data
Experiment
  • Experiment
    TEXT-QTL
  • Chromosome
    3
  • Reference
    J:66233 Brockmann GA, et al., Single QTL effects, epistasis, and pleiotropy account for two-thirds of the phenotypic F(2) variance of growth and obesity in DU6i x DBA/2 mice. Genome Res. 2000 Dec;10(12):1941-57
  • ID
    MGI:1931505
Genes
GeneAlleleAssay TypeDescription
Afpq7 visible phenotype
Afw12 visible phenotype
Notes
  • Experiment
    QTL effecting body weight, obesity and muscle weight were found on mouse Chromosomes 1, 4, 5, 7, 11, 12, 13, and 17 and for leptin on 14 and insulin on chromosome 4. The cross used in the genome wide scan included approximately 400 F2 mice from a (DU6i xDBA/2)F1 intercross. DU6i is a strain selected for high body weight. 93 microsatellite markers were analyzed in the genome wide scan. Locations of the QTL were provided by the authors and may not be equivalent to the closest microsatellites. Abdominal fat percent QTL 1 was mapped to mouse Chromosome 3 with a cM range from 23 to 37 cM. Abdominal fat weight QTL was mapped to mouse Chromosome 3 position 30 with a range from 23 to 36 cM.

    10.03.2014 - Curator Note: We had originally associated the abdominal fat weight QTL identified here, mapping to 30 cM between 23 and 36cM on mouse Chr 3, as Afw1. Afw1 was originally mapped using a different cross, an outbred cross of DU6 x DUK, in J:49578 in 1998. We consider the current mapping study a separate mapping experiment and have named the QTL identified here as Afw12.

    04.14.2015 - Curator Note: The abdominal fat percent QTL 1 (Afpq1) was originally mapped in J:49578 in 1998 using DU6 (selected for high body weight) and a DUKs female mice, which differ from the cross used here. We consider the current mapping study a separate mapping experiment and have named the QTL identified here mapping to mouse Chromosome 3 with a cM range from 23 to 37 cM as Apfq7.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory