Mapping Data

Experiment

• Experiment
  TEXT-Physical Mapping
• Chromosome
  4
• Reference
  J:59253 Simpson EH, et al., A comparative transcript map and candidates for mutant phenotypes in the Tyrp1 (brown) deletion complex homologous to human 9p21-23. Mamm Genome. 2000 Jan;11(1):58-63
• ID
  MGI:1353542

Genes

Gene	Assay Type	Description
Rorb	PCR amplified length variant	Rorb-pA, Rorb-pB
Tyrp1	other
Lurap1l	other
D4Jkn23	other
D4Jkn2	other
Mpdz	Southern analysis	MGI:1344009
D4Rck140	other
D4Rck9	other
l4Rn2	other
D4Mit115	other
Cer1	other
Zdhhc21	other
D4Mit289	other
D4Mit298	other
D4Mit276	other
D4Mit79	other
D4H9S1149	other
D4Jkn1	other

Notes

• Experiment
  Authors have analyzed the mouse Tyrp1 deletion complex using human transcripts identified from the syntenic human Chromosome 9p21-23 region. Location and expression analysis were used to exclude genes as candidates for several known phenotypes in the region. The Rorb gene was excluded as a candidate for the deletion-induced phenotypes as it was not absent from any of the deletion chromosomes. Rorb was likely to be present proximal to Tyrp1. Cer1 was found to map in the dep interval but was not proven responsible for the phenotype. The order of markers on central mouse Chromosome 4 as determined by deletion mapping was: Tyrp1 - D4Bwg0951e - D4Jkn23 - D4Jkn2 - 3' - Mpdz - 5' - D4Rck140 - D4Rck9, l4Rn2 - D4Mit115 - Cer1, dep - D4Mit289 - D4Mit298 - D4Mit276-D4Mit79 - D4H9S1149 - D4Jkn1.