Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  15
• Reference
  J:58152 Beamer WG, et al., Quantitative trait loci for bone density in C57BL/6J and CAST/EiJ inbred mice. Mamm Genome. 1999 Nov;10(11):1043-9
• ID
  MGI:1349589

Genes

Gene	Assay Type
D15Mit115	PCR amplified length variant
Bmd4	visible phenotype
D15Mit29	PCR amplified length variant
D15Mit35	PCR amplified length variant

Notes

• Experiment
  Bone mineral density (Bmd4) was measured as a quantitative trait (QTL) in a genome wide scan of 711 F2 mice in a genetic intercross involving C57BL/6J and CAST/Ei mice. C57BL/6J females express a low mineral bone density phenotype, alternatively CAST/Ei male express a high mineral bone density. Regression analysis was informative to show Bmp4 significantly associated with marker D15Mit29 within a defined QTL region bounded by markers D15Mit115 and D15Mit35. Due to the large size of the QTL region the authors did not suggest any candidate loci encoding for the Bone mineral density phenotype.