Mapping Data

Experiment

• Experiment
  TEXT-QTL
• Chromosome
  6
• Reference
  J:56444 Manenti G, et al., Linkage disequilibrium and physical mapping of Pas1 in mice. Genome Res. 1999 Jul;9(7):639-46
• ID
  MGI:1344007

Genes

Gene	Assay Type
D6Mit57	overlapping clones, PCR amplified length variant
Kras	overlapping clones, PCR amplified length variant
D6Mit14	overlapping clones, PCR amplified length variant
D6Mit303	overlapping clones, PCR amplified length variant
Y95m1f5	overlapping clones, PCR amplified length variant
Y95m5e3	overlapping clones, PCR amplified length variant
Sspn	overlapping clones, PCR amplified length variant
D6Mit200	overlapping clones, PCR amplified length variant
D6Mit137	overlapping clones, PCR amplified length variant
Pas1	resistance/susceptibility
Y94m2h10	overlapping clones, PCR amplified length variant
Y83m2c2	overlapping clones, PCR amplified length variant
D6Mit371	overlapping clones, PCR amplified length variant
D6Mit294	overlapping clones, PCR amplified length variant
D6Mit295	overlapping clones, PCR amplified length variant
D6Mit15	overlapping clones, PCR amplified length variant
D6Mit201	overlapping clones, PCR amplified length variant
Y78m6g9	overlapping clones, PCR amplified length variant
D6Mit373	overlapping clones, PCR amplified length variant
D6Mit26	overlapping clones, PCR amplified length variant
Y97m1a3	overlapping clones, PCR amplified length variant
Y88m6a6	overlapping clones, PCR amplified length variant
Y91m8f11	overlapping clones, PCR amplified length variant
D6Mit304	overlapping clones, PCR amplified length variant

Notes

• Experiment
  The authors constructed an ~1.5-2 Mb YAC contig around the Pas1 susceptibility region on mouse Chromosome 6. The order of markers in this contig was: D6Mit57 - Kras - D6Mit14 - D6Mit303 - Y95m1f5 - Y95m5e3 - Krag - D6Mit200 - D6Mit137 - Pas1 - Y94m2h10 -Y83m2c2 - D6Mit371 - D6Mit294 - D6Mit295 - D6Mit15 - D6Mit201 - Y78m6g9 - D6Mit373 - D6Mit26 - Y97m1a3 - Y88m6a6 - Y91m8f11 - D6Mit304. The authors then performed linkage disquilibrium (LD) analysis in 21 strains of known susceptibility to lung cancer. A significant LD was found for markers extending across the whole YAC contig. The two highest LD values were associated with the Kras2 and D6Mit26 markers. The possibility that two Pas1 genes might exist located near both markers could not be ruled out.