Mapping Data

Experiment

• Experiment
  CROSS
• Chromosome
  18
• Reference
  J:46242 Takaku K, et al., Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell. 1998 Mar 6;92(5):645-56
• ID
  MGI:1206110

Genes

Gene	Assay Type	Description
Adrb2	reported elsewhere
D18Mit9	reported elsewhere
Smad4	Southern analysis	Dpc4 probe
D18Mit8	reported elsewhere

Notes

• Reference
  The Dpc4/Smad4 symbol is currently Madh4 in MGD.
• Experiment
  Offspring types indicate alleles inherited from F1 parent.
  

CROSS

• Type
  Backcross, female
• Female Parent
  <c> <c> <c> <c>/<s> <s> <s> <s>
• Strain
  (C3H/HeJ-Fasl x M. spretus)F1
• Male Parent
  <c> <c> <c> <c>/<c> <c> <c> <c>
• Strain
  C3H/HeJ-Fasl/J
• Mapping Panel
  Seldin
• Allele 1
  c from C3H/HeJ-Fasl/J
• Allele 2
  s from M. spretus

CROSS Data

MC #mice	Adrb2	D18Mit9	Smad4	D18Mit8
51	c	c	c	c
52	s	s	s	s
5	c	s	s	s
1	s	c	c	c
0	c	c	s	s
2	s	s	c	c
0	c	c	c	s
3	s	s	s	c

Statistics

Marker 1	Marker 2	# Recombinants	Total	% Recombinants	Std Error
Adrb2	D18Mit9	6	114	5.263	2.091
D18Mit9	Smad4	2	114	1.754	1.230
Smad4	D18Mit8	3	114	2.632	1.499